KETAFLAM 10% INJ

KETAFLAM 10% INJ

Ketoprofen is a potent non-narcotic non-steroidal anti-inflammatory drug (NSAID), known to be better in efficacy and safety than Phenylbutazone, Diclofenac and Aspirin. It exhibits anti- inflammatory action by inhibiting cyclooxygenase and lipoxygenase pathways of arachidonic acid metabolism (COX- 1 and COX- 2), thus inhibiting the formation of prostaglandins (PGE2, thromboxane, oxygen radicals etc.).
The analgesic activity of Ketoprofen is believed to be produced by the interruption of mediators of inflammation, such as bradykinin, and prevention of their effect on peripheral pain endings. It also reduces the hyperalgesia that occurs in inflammation. Some evidence suggests that it may produce some centrally induced analgesia, such as a spinal antinociceptive effect.

Antipyretic properties of Ketoprofen are produced by the reduction of fever is believed to occur by inhibition of prostaglandins in the hypothalamus.

 

COMPOSITION:
Each ml contains-
Ketoprofen 100 mg
INDICATIONS:
– Pain, inflammation, fever and colic
– NSAID of choice during Mastitis

INDICATION:

Some specific indications, where KETAFLAM is recommended are:
Cattle, Buffaloes, Camels, Sheep and Goats:
Reducing the Pyrexia and Distress associated with bacterial and viral diseases; along with antimicrobial therapy, as and when appropriate; optimizing the recovery rate in clinical and sub- clinical Mastitis, in conjunction with antimicrobial therapy; reducing Edema of the udder associated with calving; supportive treatment of Milk Fever associated with calving; lameness of traumatic origin, osteitis, arthrosis, arthritis, tendinitis, laminitis, and myositis; post- surgical inflammation.
Horses:
Alleviation of inflammation and pain associated with musculo-skeletal disorders. It is also indicated for the alleviation of visceral pain associated with Colic; reducing Pyrexia and Distress associated with bacterial and viral diseases; along with antimicrobial therapy, as and when appropriate; lameness and trauma related painful conditions, spavin, osteitis, navicular disease, tendinitis, bursitis, laminitis, myositis; post- surgical inflammation
Dogs and cats:
Fever; pain; post- surgical inflammation; arthritis

DOSAGE AND ADMINISTRATION:

  • Cattle, Buffaloes, Camels, Sheep & Goats:
    3mg Ketoprofen per kg bw (1ml Ketaflam per 33 kg
    bw), by IM, IV or SC route, once daily for 3 to 5 days
  • Horses: 2.2 mg Ketoprofen per kg bw (1ml Ketaflam
    per 45 kg bw), by IV route, once daily for 3 to 5 days
  • Dogs & Cats: 2 mg Ketoprofen per kg bw (1ml
    Ketaflam / 50 kg bw), by IM, SC or IV route once daily
    for 3-5 days

WITHDRAWAL TIME:

Milk- Nil
Meat- 4 days

PACKING:

50ml, 100 ml

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